To explore the effect of prescription of traditional sports regimen with different amounts of exercise on improving depression and sleep quality of college students. Depression Screening Scale (PHQ-9) and Zung’s Self-rating Depression Scale (SDS) were used to screen students with mild depression, who were randomly divided into control group, experimental group 1 (moderate exercise intensity, 30min each time, 5 times a week,) and experimental group 2 (moderate exercise intensity, 60min each time, 5 times a week). The exercise prescription intervention with different exercise amount was performed for 16 weeks. Compared with before exercise, the total scores of SDS and PSQI of the two experimental groups decreased significantly after 8 weeks of intervention; after 16 weeks of intervention, the total scores of SDS and PSQI of the experimental groups were obviously different (P < 0.05) compared with 8 weeks of intervention; after 8 weeks of training cessation, the total scores of SDS and PSQI of the experimental groups were increased, but however, significant decrease in the total scores still can be seen compared with those before the experiment(P<0.05). Compared with the control group, after 8 weeks of intervention, 16 weeks of intervention and 8 weeks of training cessation, the total scores of SDS and PSQI of the two experimental groups were significantly reduced and the effect of experimental group 2 on improving PSQI score of college students was significantly better than that of experimental group 1.Traditional sports regimen intervention can improve college students’ depression and improve their sleep quality, and it can still maintain the effect after stopping training for 8 weeks; exercise intervention of 60 minutes each time, 5 times a week, has better effect on improving college students’ sleep quality than that of 30 minutes each time, 5 times a week.
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