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Data correlations between gender, cytomegalovirus infection and T cells, NK cells, and soluble immune mediators in elderly humans

机译:性别,巨细胞病毒感染和T细胞,NK细胞和老年人可溶性免疫介质之间的数据相关性

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摘要

We describe a cohort of 50 elderly subjects, age at least 70 years. We present gender-specific findings in T lymphocyte markers and soluble immune mediators. We show the correlation between cytomegalovirus infection status with CD56 dim NK cell responses to a variety of stimuli and with CD56 bright /CD56 dim NK cell ratio. We also present the correlation of retinol binding protein (RBP)?4 plasma levels with NK cell responses and we explore the relationship between gender and adiponectin, 25(OH)D (vitamin D), and RBP4 in affecting CD56 dim NK cell responses. These data are discussed in Al-Attar et al. (2016) .
机译:我们描述了50个老年人的队列,年龄至少为70年。我们在T淋巴细胞标志物和可溶性免疫介质中呈现性别特异性发现。我们展示了CD56昏暗的NK细胞对各种刺激和CD56亮/ CD56暗NK细胞比的CD56暗腔细胞感染状态之间的相关性。我们还介绍了视黄醇结合蛋白(RBP)α的相关性与NK细胞反应的4次血浆水平,我们探讨了性别和脂肪蛋白,25(OH)D(维生素D)之间的关系,以及影响CD56昏暗的细胞反应的RBP4。这些数据在Al-Attar等人中讨论。 (2016)。

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