Response to Comment on “Direct Hematological Toxicity and Illegitimate Chromosomal Recombination Caused by the Systemic Activation of CreERT2”

摘要

I am writing in response to a letter from Uhmann et al. commenting on our recent publication in The Journal of Immunology ([1][1]), where we demonstrated hematological toxicity in tamoxifen-treated R26CreERT2 mice and accordingly proposed that a group of tamoxifen-treated CreERT2 mice (without the