首页> 外文期刊>The Internet Journal of Dermatology >Darier's Disease: Report Of A New Case With A Rare Clinical Appearance
【24h】

Darier's Disease: Report Of A New Case With A Rare Clinical Appearance

机译:道尔氏病:罕见临床表现的新病例报告

获取原文
           

摘要

Patient with localized keratotic lesions and revealing histologic features of dyskeratotic acantholysis have been rarely reported. There is still some controversy regarding the appropriate nosologic placement of this entity. Some believe it represent a variant of epidermal nevus, while others argue it is a genetic mosaic of generalized Darier`s Disease. We report a case of a 67-years-old man who presented with a 1-year history of pruritic, reddish-brown papules on the abdomen. The lesions resolved in the winter and again occurred in the summer months. Physical exam revealed reddish-brown papules with verrucous texture on the abdomen. There were no other cutaneous and membranous signs. Diagnosis of Darier`s Disease was histologically evident. Case Report A 67-year-old man presented with reddish-brown papules.(Fig. 1) The patient presented with a 1-year generalized pruritus (specially the abdomen. Subsequent, red papules occurred which resolved after a while. Six months later (in the summer), lesions occurred again in the same areas. Physical examination revealed papules on the abdomen, longitudinal band and slightly subungual hyperkeratosis of the left 4th fingernail. General physical examination was normal. Other family members, including his 15-year-old son and 21-year-old daughter had no problems.
机译:极少报告局部角化病变和显示角化棘层松解症的组织学特征的患者。关于该实体在适当的肿瘤学位置上仍存在一些争议。一些人认为它代表了表皮痣的变体,而另一些人则认为这是广义Darier病的遗传镶嵌。我们报告了一例67岁的男性,该男性在腹部出现1年瘙痒,红褐色丘疹史。病变在冬季消退,并在夏季再次发生。体格检查发现腹部出现红褐色丘疹,疣状纹理。没有其他皮肤和膜状体征。在组织学上诊断达里尔氏病是明显的。病例报告一名67岁男性出现红褐色丘疹(图1),患者出现1年期全身瘙痒(特别是腹部),随后出现红色丘疹,此后一段时间后消退,六个月后。 (夏季)病变在同一区域再次发生,体格检查发现左第4指甲的腹部丘疹,纵带和轻微的趾下角化过度,一般体检正常,其他家庭成员,包括他15岁大儿子和21岁的女儿没有问题。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号