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Hypocholesterolemic efficacy of royal jelly in healthy mild hypercholesterolemic adults

机译:蜂王浆对健康轻度高胆固醇血症成年人的降胆固醇功效

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Abstract Context: Royal jelly (RJ) has been reported for its health promoting factors such as antioxidant, anti-inflammatory and lipid lowering activities. Objective: The present randomized, placebo-controlled study examines the hypolipidemic beneficial effect of RJ through evaluating anthropometric measurements, lipid profile and various hormone levels in mildly hypercholesterolemic participants. Materials and methods: Forty subjects with mild hypercholesterolemia (180–200?mg/dL) were randomly selected and divided into two groups as experimental or placebo, who requested to intake nine capsules (350?mg/capsule) of RJ or placebo/day, respectively, for three months with one month of follow-up without any supplementation. Results: No significant changes were noted in any of the anthropometric parameters like body weight, waist and body fat. The serum total cholesterol (TC; 207.05–183.15?mg/dL) and low-density lipoprotein cholesterol (LDL-c; 126.44–120.31?mg/dL) levels were reduced significantly (p?p?
机译:摘要背景:蜂王浆(RJ)具有促进健康的作用,如抗氧化剂,抗炎和降脂活性。目的:这项随机,安慰剂对照的研究通过评估轻度高胆固醇血症参与者的人体测量指标,脂质分布和各种激素水平,检查了RJ的降血脂有益作用。材料和方法:随机选择40例轻度高胆固醇血症(180-200?mg / dL)受试者,分为实验组或安慰剂两组,每组每天服用9粒RJ或安慰剂(350mg /胶囊)。分别进行三个月和一个月的随访,无需任何补充。结果:在任何人体测量学参数(如体重,腰围和体脂)中均未发现明显变化。血清总胆固醇(TC; 207.05–183.15?mg / dL)和低密度脂蛋白胆固醇(LDL-c; 126.44–120.31?mg / dL)水平显着降低(p?p?<?0.05)。性激素,例如硫酸脱氢表雄酮(DHEA-S; 1788.09–1992.31?ng / mL)。此外,摄入RJ不会引起任何肝或肾损害。讨论与结论:持续三个月的RJ干预通过提高DHEA-S的水平大大降低了TC和LDL-c的水平,从而降低了患心血管疾病(CVD)的风险。

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