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Evaluation of thin layer chromatography image analysis method for irradiated chlorpromazine quantification

机译:薄层色谱图像分析方法在辐照氯丙嗪定量分析中的应用

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We report the use of TLC image analysis software, JustTLC, foridentification and quantitative evaluation of the photoproducts generated by theirradiation of Chlorpromazine water solutions with a 266 nm laser beam. The percentconcentrations resulting for photoproducts from TLC analysis were compared withthe relative concentrations of those identified by LC-TOF/MS measurements. Thespots on the analyzed TLC plate were attributed to the corresponding photoproducts.Although LC-MS methods are more accurate, TLC can be successfully used toquantify the photoproducts obtained after exposure to UV laser radiation.
机译:我们报告了TLC图像分析软件JustJTL的使用,对通过用266 nm激光束照射氯丙嗪水溶液产生的光产物进行鉴定和定量评估。将通过TLC分析得到的光产物的百分比浓度与通过LC-TOF / MS测量确定的相对浓度进行比较。经分析的TLC板上的斑点归因于相应的光产物。尽管LC-MS方法更准确,但TLC可以成功地用于量化暴露于UV激光辐射后获得的光产物。

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