Effect of transcutaneous electrical acupoint stimulation on the EC50 of remifentanil suppressing responses to tracheal extubation in elderly patients

摘要

Transcutaneous electrical acupoint stimulation (TEAS) is a emerging treatment which combines transcutaneous electrical nerve stimulation with traditional acupoint therapy. The present study was aimed to evaluate the effect of TEAS on the effective concentration (ECsub xmlns:mrws="of remifentanil suppressing tracheal extubation response in elderly patients. Fifty-three patients undergoing spine surgery were randomly divided into 2 groups: control group (group C, n = 26) and transcutaneous electrical acupoint stimulation group (group TEAS, n = 27). The ECsub xmlns:mrws="values for remifentanil TCI were determined using sequential method and probit analysis. The remifentanil ECsub xmlns:mrws="of that suppressed responses to extubation during anesthetic emergence was 1.20 ng/mL in group TEAS, a value that was significantly lower than the 1.64 ng/mL needed by patients in group C. The TEAS can enhance the efficacy of remifentanil on suppressing responses to tracheal extubation in elderly patients, the ECsub xmlns:mrws="of remifentanil can reduce approximately 27% compared with group C.