首页> 外国专利> Isolated polypeptide, fusion protein, isolated polynucleotide molecule, expression vector, cultured cell, antibody or antibody fragment, and, methods for producing a protein, for producing an antibody, for stimulating an immune response in a mammal, for expanding cells hematopoietic and hematopoietic cell progenitors, to detect the presence of rna zcytor17lig and zcytor17lig in a biological sample, to kill cancer cells, to inhibit zcytor17lig-induced proliferation or differentiation of hematopoietic cells and hematopoietic cell progenitors, to reduce inflammation by zcytor17lig to suppress an inflammatory response in a mammal with inflammation, to treat a mammal affected by an inflammatory disease and to detect inflammation in a patient

Isolated polypeptide, fusion protein, isolated polynucleotide molecule, expression vector, cultured cell, antibody or antibody fragment, and, methods for producing a protein, for producing an antibody, for stimulating an immune response in a mammal, for expanding cells hematopoietic and hematopoietic cell progenitors, to detect the presence of rna zcytor17lig and zcytor17lig in a biological sample, to kill cancer cells, to inhibit zcytor17lig-induced proliferation or differentiation of hematopoietic cells and hematopoietic cell progenitors, to reduce inflammation by zcytor17lig to suppress an inflammatory response in a mammal with inflammation, to treat a mammal affected by an inflammatory disease and to detect inflammation in a patient

机译:分离的多肽,融合蛋白,分离的多核苷酸分子,表达载体,培养的细胞,抗体或抗体片段,以及产生蛋白质,产生抗体,刺激哺乳动物的免疫应答,扩大造血细胞和造血细胞的方法祖细胞,可检测生物样品中RNA zcytor17lig和zcytor17lig的存在,杀死癌细胞,抑制zcytor17lig诱导的造血细胞和造血细胞祖细胞的增殖或分化,通过zcytor17lig减轻炎症,从而抑制哺乳动物的炎症反应伴发炎,以治疗受发炎疾病影响的哺乳动物,并检测患者的炎症

摘要

"ISOLATED POLYPEPTIDE, FUSION PROTEIN, ISOLATED POLYNUCLEOTIDE MOLECLE, EXPRESSION VECTOR, CULTURED CELL, ANTIBODY OR FRAGMENT, AND, METHODS TO MAKE A PROTEIN A PROPULY TO RESPONSE MUSDLE CELLS hematopoietic AND PARENTS CELLS hematopoietic TO DETECT THE RNA ZCYTOR17LIG AND ZCYTOR17LIG pRESENCE IN A SAMPLE biological, TO KILL CELLS cancer, to inhibit proliferation INDUCED ZCYTOR17LIG or cell differentiation hematopoietic AND PARENTS CELLS hematopoietic, to reduce inflammation INDUCED BY ZCYTORI7LIG, TO SUPPRESS AN INFLAMMATORY RESPONSE IN AN INFLAMMED MAMMER, TO TREAT A MAMMER ACHIEVED BY AN INFLAMMATORY DISEASE AND TO DETECT INFLAMMATION IN A PATIENT. " The present invention relates to zcytor17lig polypeptide, polypeptide and anti-zcytor17 antibody molecules. Zcytor17lig is a new cytokine. Polypeptides may be used with methods of stimulating the immune system, and proliferating and / or developing hematopoietic cells in vitro and in vivo. The present invention also includes methods for making the protein, uses for it and antibodies to it.
机译:“分离的多肽,融合蛋白,分离的多聚核苷酸,表达载体,培养的细胞,抗体或片段,以及使蛋白充分响应造血和造血干细胞的方法,并使得Z细胞在z17上表达了充分的能力生物,以杀死癌细胞,抑制ZCYTOR17LIG诱导的增殖或造血细胞分化,并造血的父母,以减少ZCYTORI7LIG诱导的炎症,抑制发炎的妈妈的炎症反应,治疗妈妈的病灶并治愈对患者的炎症反应本发明涉及zcytorl7lig多肽,多肽和抗zcytorl7抗体分子。 Zcytor17lig是一种新的细胞因子。多肽可以与在体外和体内刺激免疫系统和增殖和/或发育造血细胞的方法一起使用。本发明还包括该蛋白质的制备方法,其用途和抗体。

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