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Blast Testing Issues and TBI: Experimental Models That Lead to Wrong Conclusions

机译:爆破测试问题和TBI:导致错误结论的实验模型

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Over the past several years, we have noticed an increase in the number of blast injury studies published in peer-reviewed biomedical journals that have utilized improperly conceived experiments. Data from these studies will lead to false conclusions and more confusion than advancement in the understanding of blast injury, particularly blast neurotrauma. Computational methods to properly characterize the blast environment have been available for decades. These methods, combined with a basic understanding of blast wave phenomena, enable researchers to extract useful information from well-documented experiments. This basic understanding must include the differences and interrelationships of static pressure, dynamic pressure, reflected pressure, and total or stagnation pressure in transient shockwave flows, how they relate to loading of objects, and how they are properly measured. However, it is critical that the research community effectively overcomes the confusion that has been compounded by a misunderstanding of the differences between the loading produced by a free field explosive blast and loading produced by a conventional shock tube. The principles of blast scaling have been well established for decades and when properly applied will do much to repair these problems. This paper provides guidance regarding proper experimental methods and offers insights into the implications of improperly designed and executed tests. Through application of computational methods, useful data can be extracted from well-documented historical tests, and future work can be conducted in a way to maximize the effectiveness and use of valuable biological test data.
机译:在过去的几年中,我们注意到在同行评审的生物医学期刊中使用不当构思的实验发表的爆炸伤害研究的数量有所增加。这些研究的数据将导致错误的结论,并且在了解爆炸伤,特别是爆炸神经创伤方面,会比前进的结果更加混乱。正确描述爆炸环境特征的计算方法已有数十年历史了。这些方法与对爆炸波现象的基本理解相结合,使研究人员能够从有据可查的实验中提取有用的信息。这种基本理解必须包括瞬态冲击波流中静压力,动压力,反射压力以及总压力或滞止压力的差异和相互关系,它们与物体的负载有何关系,以及如何对其进行正确测量。然而,至关重要的是,研究界必须有效地克服由于对自由场爆炸冲击波产生的载荷与常规冲击管产生的载荷之间的差异的误解而加剧的混乱。爆破垢的原理已经确立了数十年,如果正确应用,将对修复这些问题起到很大作用。本文提供了有关正确的实验方法的指南,并提供了对设计和执行不正确的测试的含义的见解。通过应用计算方法,可以从有据可查的历史测试中提取有用的数据,并且可以以最大程度地提高有效性和使用有价值的生物测试数据的方式开展未来的工作。

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