首页> 外文学位 >Mechanics of blast loading on post-mortem human and surrogate heads in the study of traumatic brain injury (TBI) using experimental and computational approaches.
【24h】

Mechanics of blast loading on post-mortem human and surrogate heads in the study of traumatic brain injury (TBI) using experimental and computational approaches.

机译:在使用实验和计算方法研究颅脑损伤(TBI)的尸体和尸体头部后,爆炸载荷的力学原理。

获取原文
获取原文并翻译 | 示例

摘要

Blast induced neurotrauma (BINT) has been designated as the "signature injury" to warfighters in the recent military conflicts. The occurrence of traumatic brain injury (TBI) in blasts is controversial in the medical and scientific communities because the manifesting symptoms occur without visible injuries. Whether the primary blast waves alone can cause mechanical insult that is comparable to existing traumatic brain injury thresholds is still an open question, and this work is aimed to address this issue.;In the first part of this dissertation, mechanics of primary blast loading on Realistic Explosive Dummy (RED) head with and without helmets is studied using experiments and a validated numerical model. It is shown that geometry of the head and helmet, their configurations and orientations with respect to the direction of the blast govern the flow dynamics around the head; these factors in turn determine the surface pressures. The blast wave can focus under the helmet if there is a gap between the head and the helmet leading to an increase in surface pressures beneath the focused regions.;In the second part of this dissertation, the response of post-mortem human specimen (PMHS) heads is studied. Three PMHS heads are subjected to primary blast of varying peak incident intensities or overpressures (70 kPa, 140 kPa and 200 kPa). When the incident blast intensity is increased, there is a statistically significant increase in the peak intracranial pressure (ICP) and total impulse (p<0.05). Further, for blast overpressures of 140 kPa and 200 kPa, ICP values exceed brain injury thresholds available in the literature based on blunt impacts. From the parametric studies on the validated human head model, it is seen that the wave propagation through skin-skull-brain parenchyma plays prominent role in governing ICP-time histories. The effect of helmets on PMHS head is also analyzed. The results suggest that based only on ICP blast mitigation offered by the current helmets may be marginal, if at all.
机译:在最近的军事冲突中,爆炸诱发的神经创伤(BINT)被指定为对战士的“标志性伤害”。在爆炸性脑损伤(TBI)的发生在医学和科学界引起争议,因为出现的症状没有明显的伤害就发生了。单独的初级爆炸波是否会导致与现有的颅脑外伤阈值相当的机械损伤仍是一个悬而未决的问题,这项工作旨在解决这个问题。使用实验和经过验证的数值模型研究了带头盔和不带头盔的逼真的爆炸性虚拟人(RED)头。结果表明,头部和头盔的几何形状,它们相对于爆炸方向的构造和方向决定着头部周围的流动动力学。这些因素反过来决定了表面压力。如果头部和头盔之间存在间隙,导致聚焦区域下方的表面压力增加,则爆炸波可以在头盔下方聚焦。在本文的第二部分,尸体标本(PMHS)的响应)脑袋研究。三个PMHS喷头受到一次峰值冲击强度或过压(70 kPa,140 kPa和200 kPa)变化的一次冲击波。当爆炸冲击波强度增加时,颅内压峰值(ICP)和总冲动在统计学上显着增加(p <0.05)。此外,对于140 kPa和200 kPa的爆炸超压,ICP值超过了文献中基于钝器冲击的脑损伤阈值。从对经过验证的人头模型的参数研究中可以看出,通过皮肤-颅脑实质的波传播在控制ICP时间历史方面起着重要作用。还分析了头盔对PMHS头部的影响。结果表明,仅基于当前头盔提供的ICP爆炸缓解,即使有的话,也可能是微不足道的。

著录项

  • 作者

    Ganpule, Shailesh Govind.;

  • 作者单位

    The University of Nebraska - Lincoln.;

  • 授予单位 The University of Nebraska - Lincoln.;
  • 学科 Applied Mechanics.;Biophysics Biomechanics.;Engineering General.
  • 学位 Ph.D.
  • 年度 2013
  • 页码 288 p.
  • 总页数 288
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号