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首页> 外文期刊>Evidence-based complementary and alternative medicine: eCAM >Evaluating the Quality of Randomized Controlled Trials that Examine the Efficacy of Natural Health Products: A Systematic Review of Critical Appraisal Instruments
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Evaluating the Quality of Randomized Controlled Trials that Examine the Efficacy of Natural Health Products: A Systematic Review of Critical Appraisal Instruments

机译:评价检查天然保健品功效的随机对照试验的质量:关键评估工具的系统评价

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摘要

The purpose of this project was to conduct a systematic review to identify instruments designed to evaluate the quality of randomized controlled trials (RCTs) of natural health products (NHPs). Instruments were examined for inclusion of items assessing methods, identity and content of the NHP, generalizability of results and instructions for use. Online databases, websites, textbooks and reference lists were searched to identify instruments. Relevance assessment and data extraction of articles were completed by two investigators and disagreements were settled by the third investigator. Data were analyzed using descriptive statistics. Of the 4442 citations identified, 29 were potentially relevant with 16 meeting the criteria for inclusion. None of the instruments stated they were validated; content in the four areas of interest varied considerably. The most common items included randomization sequence generation (100%), blinding (100%), allocation concealment (75%) and participant flow (75%). Only nine of the NHP instruments included at least one item to appraise the specific content of the NHP. The CONSORT Statement for Herbal Interventions most closely addressed the four areas of interest; however, this instrument was specific for herbs. There is a need for the development of a validated instrument for assessment of the quality of RCTs that would be useful for herbs as well as other NHPs.
机译:该项目的目的是进行系统的审查,以确定旨在评估天然保健品(NHP)随机对照试验(RCT)质量的仪器。检查了仪器是否包括项目评估方法,NHP的身份和内容,结果的概括性以及使用说明。搜索在线数据库,网站,教科书和参考书目以识别工具。文章的相关性评估和数据提取由两名调查员完成,分歧由第三名调查员解决。使用描述性统计数据分析数据。在确定的4442条引用中,有29条与16条符合纳入标准的潜在相关。没有工具表明它们已经过验证;四个感兴趣领域的内容差异很大。最常见的项目包括随机序列生成(100%),致盲(100%),分配隐藏(75%)和参与者流(75%)。只有9种NHP文书包括至少一项评估NHP特定内容的项目。 CONSORT草药干预声明最贴切地关注了四个感兴趣的领域:但是,该仪器专用于草药。有必要开发一种经过验证的仪器,以评估RCT的质量,这将对草药以及其他NHP有用。

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