Leonardo da Vinci’s Virgin of the Rocks Perhaps the first depiction of congenital vascular malformation syndrome

摘要

Leonardo da Vinci is considered amongst the greatest geniuses and innovators ofall time. His work as an artist during the renaissance has demonstrated his abilityto depict anatomy and pathology with a degree of accuracy that was unparalleled(Ashrafan 2011a, 2013). Amongst his works, Leonardo painted the piece known asthe Virgin of the Rocks (also known as the Madonna of the Rocks) twice; the frst versionis dated to approximately 1491/2-9 (now based at the Louvre, Paris) and the secondis dated to approximately 1506-8 (now based at The National Gallery, London).