Synthesis of Some Novel Bis 1,3,4-OxadiazoleFused Azo Dye Derivatives as PotentAntimicrobial Agents

摘要

3,5-bis(5-(furan-2-yl)-1,3,4-oxadiazol-2-yl)azo dyes were synthesized by multistep reaction sequences, which is diazotized and coupled with different napthols and quinoline. Structure of newly synthesized compounds were characterized and confirmed by IR, NMR and Mass spectral studies. The newly synthesized azo dye fused with (5-(furan-2-yl)-1,3,4-oxadiazole) were screened for their acute toxicity and gross behavioral studies and in-vitro anti-microbial activity. Synthesized compounds exhibit significant biological activity and can certainly hold greater promise in discovering safer biologically active molecules.