Antidiabetic Effect of Nono (A Nigerian Fermented Milk) on Alloxan-Induced Diabetic Rats

摘要

The effect of Nono (a Nigerian fermented milk) on diabetic situation in rats, induced by intraperitonial injection of alloxan monohydrate is reported. Nono administration for 4 weeks lowered the raised plasma glucose concentration of diabetic rats ; restoring it to the non diabetic rat level. The low tissue protein and raised plasma protein concentrations; hyperlipidemia; and hypercholesterolemia consequential on diabetic induction were reversed to the normal level by the Nono administration. The reversals of these effects of diabetes may be due to the lowering of the plasma glucose concentration by Nono or direct activity of either the bacteria or milk components of Nono on these substances. The results indicate that consumption of Nono produced by wild strain lactic acid bacteria may be helpful in the management of diabetes.