The Changing Pattern of Kaposi’s Sarcoma in Sudan: Experience in a Single Center

摘要

The first cases of Kaposi’s sarcoma were described by Moritz Kaposi, a Hungarian dermatologist, in 1872. Ever since many facts about Kaposi’s sarcoma were addressed in the world literature. These included epidemiology, clinical manifestations, etiology, pathology, pathogenesis, and treatment. The tumour has been divided into several subtypes that include the original classic, Endemic (African) Kaposi's sarcoma, Immunosuppression-Associated, Transplantation- Associated Kaposi's Sarcoma and Epidemic or AIDS-Associated, Kaposi's sarcoma. The tumour is caused by the Human Papilloma Virus (HPV). In this communication, we describe our experience with Kaposi’s sarcoma in Sudan. Before the HIV pandemic, the cases were of the classic and endemic African subtypes. After the HIV pandemic, we encountered AIDS-Associated KS and KS in renal transplant patients under immunosuppressive therapy. ? The classic and African types are still also seen.? The clinical manifestations, the pathology, and pathogenesis of KS in Sudan are described and discussed.