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Characterization and Synergistic Antifungal Evaluation of a Food Grade Microemulsion System against Aspergillus flavus

机译:食品级黄曲霉微乳体系的表征和协同抗真菌评价

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In this study, we aim to study the possibility of enhancing the antifungal application of microemulsions in food industry. The physicochemical properties of multi-component microemulsions containing Cinnamon Essential Oil (CEO), ethanol, Tween 80, water and lactic acid have been studied. Lactic acid showed positive effect on oil solubilization and the formation of U-type microemulsion. Four microemulsion formulations were selected and used for particle size distribution and viscosity measurements. The synergistic antifungal effects of CEO and lactic acid on Aspergillus flavus were studied by measurements of Fractional Inhibitory Concentration Index (FICI). Antifungal tests suggested that the microemulsions inhibited the viable fungal spores and the mycelium growth effectively as the Minimal Inhibitory Concentration (MIC) of the microemulsions ranged from 4 mg/mL to 11 mg/mL. The addition of lactic acid in CEO/ethanol/Tween 80/water system also greatly improved the antifungal activity of microemulsions. It was found that the CEO had synergistic antifungal activities in combination with lactic acid for the value of FICI was ranged from 0.30 to 0.35. This study shows the possibility of enhancing the antifungal application of microemulsions in food industry.
机译:在这项研究中,我们旨在研究在食品工业中增强微乳液抗真菌应用的可能性。研究了含有肉桂精油(CEO),乙醇,吐温80,水和乳酸的多组分微乳的理化性质。乳酸对油的增溶和U型微乳液的形成具有积极作用。选择了四种微乳液配方,并将其用于粒度分布和粘度测量。通过测定分数抑制浓度指数(FICI),研究了CEO和乳酸对黄曲霉的协同抗真菌作用。抗真菌试验表明,微乳剂的最小抑菌浓度(MIC)范围为4 mg / mL至11 mg / mL,可有效抑制活菌孢子和菌丝体的生长。在CEO /乙醇/ Tween 80 /水系统中添加乳酸也极大地改善了微乳液的抗真菌活性。发现CEO具有与乳酸组合的协同抗真菌活性,因为FICI的值在0.30至0.35的范围内。这项研究表明了增强微乳剂在食品工业中抗真菌应用的可能性。

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