Yawning is found in almost all animals including reptiles. Various theories have tried to describe yawning as a reflex to increase arousal & alertness in an exhausted and tired state. Several Medications are known to give rise to excessive yawning. This unusual, under recognised and usually ignored side effect can cause the sufferers to have severe problems. SSRI’s which are a well-established first line treatment for depression can lead to intractable yawning .We hereby present a case of intractable yawning in an individual on an SSRI namely fluoxetine. There was a clear temporal relationship i.e. starting Fluoxetine led to intractable Yawning and its discontinuation relieved it.
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