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The study of etiological and demographic characteristics of acute household accidental poisoning in children - a consecutive case series study from Pakistan

机译:儿童急性家庭意外中毒的病因和人口学特征研究-巴基斯坦的连续病例系列研究

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Background To determine the agents of poisoning and demographic distribution of children brought to Civil Hospital Karachi (CHK) with a history of accidental poison intake and to examine the factors associated with it. Methods This hospital based descriptive study of first 100 patients from both sexes who presented to Pediatric department, CHK from 1st January 2006 till 31st December 2008 with exposure to a known poisonous agent and fulfilling other inclusion criteria were included in the study. Data regarding their demographic profile and potential risk factors was collected on a well structured proforma, cases were followed until discharge or expiry. Data was analyzed using frequencies, proportions, group means, median and standard deviations. Results The male to female ratio in our study was 1.2:1, with kerosene (50%) being the most common household agent followed by medicines (38%), insecticides (7%) and bathroom cleaners (5%). Factors such as mother's education level, number of siblings and storage place of poison correlated significantly with the cases of accidental poisoning. Most of the children (70%) presented within 3 hours of ingestion. Dyspnea was the most common symptom observed. The mortality rate in our study was 3%. Conclusions Children belonging to age group 2-3 years are the most susceptible both in terms of morbidity and mortality. Preventive strategies need to be adopted at a national level to spread awareness among parents.
机译:背景技术确定被带入卡拉奇(CHK)民事医院的儿童中毒的原因和人口分布,该儿童有意外的毒物摄入史,并研究与之相关的因素。方法对2006年1月1日至2008年12月31日期间在CHK医院儿科就诊的首例100例男女患者进行描述性研究。药物和满足其他纳入标准的药物也纳入研究。在结构良好的形式表上收集有关其人口统计资料和潜在危险因素的数据,并跟踪病例直至出院或到期。使用频率,比例,组均值,中位数和标准差分析数据。结果在我们的研究中,男女比例为1.2:1,其中最常用的是煤油(50%),其次是药物(38%),杀虫剂(7%)和浴室清洁剂(5%)。母亲的受教育程度,兄弟姐妹的数量和毒物的存放地点等因素与意外中毒的病例有显着相关。大多数儿童(70%)在摄入后3小时内出现。呼吸困难是最常见的症状。我们研究中的死亡率为3%。结论无论是发病率还是死亡率,属于2-3岁年龄段的儿童都是最易感的。需要在国家一级采取预防策略,以在父母之间传播意识。

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