Anti-fatigue effects of polyphenols extracted from Areca catechu L. husk and determination of the main components by high performance capillary electrophoresis

摘要

This study explored the antioxidant potential and anti-fatigue effects of polyphenols extracted from Areca Catechu L. husk (AHP). Radicals scavenging activities and reducing power were determined to evaluate the antioxidant potentials in vitro and a weight loaded forced swimming test (WFST) was used to estimate the anti-fatigue effect. The main components of AHP were analyzed by HPCE at last. The AHP possessed considerable antioxidant effects on scavenging DPPH, ABTS radicals and reducing power. All the tested bio parameters of the mice which received the high dose of AHP (20 mg/kg) were improved. The AHP was mainly composed of (–)-epicatechin, (+)-catechin, keampferol, naringenin, ferulic acid and chromogenic acid. These results suggest that the AHP can be a promising source as a natural antioxidant and anti-fatigue material for the use in functional foods even medicines.