Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal data

Dagmar Jírová; David Basketter; Manfred Liebsch; Hana Bendová; Kristina Kejlová; Marie Marriott; Helena Kandárová

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Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal data

机译：人皮肤刺激贴片试验数据与体外皮肤刺激试验和动物数据的比较

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Background: Efforts to replace the rabbit skin irritation test have been underway for many years, encouraged by the EU Cosmetics Directive and REACH. Recently various in vitro tests have been developed, evaluated and validated.

机译：背景：在欧盟化妆品指令和REACH的鼓励下，替代兔子皮肤刺激性试验的努力已经进行了很多年。最近，已经开发，评估和验证了各种体外测试。

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来源
《Contact Dermatitis》 |2010年第2期|109-116|共8页
作者
Dagmar Jírová; David Basketter; Manfred Liebsch; Hana Bendová; Kristina Kejlová; Marie Marriott; Helena Kandárová;
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作者单位

National Institute of Public Health Prague Czech Republic;

DABMEB Consultancy Ltd. Sharnbrook UK;

ZEBET Federal Institute for Risk Assessment Berlin Germany;

Safety and Environmental Assurance Center Unilever Colworth Laboratory Bedford UK;

MatTek Corporation MA Ashland USA;

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原文格式 PDF
正文语种 eng
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关键词
4-hr human patch test; rabbit test; reconstructed human epidermis model; skin irritation;

机译：4小时人体贴片试验;兔试验;重建人表皮模型;皮肤刺激;
入库时间 2022-08-17 14:15:42

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专利

1. Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal data. [J] . Jirova D, Basketter D, Liebsch Contact dermatitis . 2010,第2期

机译：人皮肤刺激贴剂测试数据与体外皮肤刺激试验和动物数据的比较。
2. Comparative assessment of 24-hr primary skin irritation test and human patch test data with in vitro skin irritation tests according to OECD Test Guideline 439 (for quasi-drugs in Japan) [J] . Mariko Sugiyama, Masaharu Akita, Nathalie Alépée, The Journal of toxicological sciences . 2018,第12期

机译：根据OECD测试指南439（针对日本的准药品），对24小时原发性皮肤刺激性试验和人斑贴试验数据与体外皮肤刺激性试验进行比较评估
3. Comparative assessment of 24-hr primary skin irritation test and human patch test data with in vitro skin irritation tests according to OECD Test Guideline 439 (for quasi-drugs in Japan) [J] . Sugiyama Mariko, Akita Masaharu, Alepee Nathalie, The Journal of toxicological sciences . 2018,第10a12期

机译：根据经合组织试验指南439（日本对准药物的体外皮肤刺激试验，对24小时原发性皮肤刺激试验和人贴剂测试数据的比较评估
4. In Vitro Skin Irritation Assays: Relevance to Human Skin [C] . Sunita Patil, Jeff Harvell, Howard I. Maibach NATO Advanced Study Institute on the Modulation of Cellular Responses in Toxicity . 1995

机译：体外皮肤刺激测定：与人体皮肤的相关性
5. In vitro cytotoxicity and skin irritation testing of antimicrobial conjugated electrolytes: Interactions with mammalian cells. [D] . Wilde, Kristin N. 2012

机译：抗菌共轭电解质的体外细胞毒性和皮肤刺激性测试：与哺乳动物细胞的相互作用。
6. An In Vitro Skin Irritation Test (SIT) using the EpiDerm Reconstructed Human Epidermal (RHE) Model [O] . Helena Kandárová, Patrick Hayden, Mitchell Klausner, 2009

机译：使用EpiDerm重建的人类表皮（RHE）模型进行的体外皮肤刺激试验（SIT）
7. ESAC Opinion on the validation study of the epiCS® Skin Irritation Test (SIT) based on the EURL ECVAM/ OECD Performance Standards for in vitro skin irritation testing using Reconstructed human Epidermis (RhE) [O] . CARMICHAEL Neil, BORLAK Jürgen, CLEWELL III Harvey, 2016

机译：ESAC关于基于EURL ECVAM / OECD性能标准的EpiCS®皮肤刺激性测试（SIT）的验证研究的意见，该标准用于使用重组人表皮（RhE）进行体外皮肤刺激性测试
8. Results of 2 Algal Studies, a Daphnid and Fish Study, Eye Irritation and Skin Sensitization Studies, an In Vitro Ames Assay in Salmonella and a Chromosomal Aberration Assay in Human Peripheral Blood Lymphocytes with Benzoic Acid, 2(chlorosulfonyl)-3-Methyl and Methyl Ester. [R] . 2009

机译：2种藻类研究，水蚤和鱼类研究，眼睛刺激和皮肤致敏研究的结果，沙门氏菌的体外ames测定和人类外周血淋巴细胞中的染色体畸变测定，苯甲酸，2（氯磺酰基）-3-甲基和甲基酯。

Comparison of human skin irritation patch test data with in vitro skin irritation assays and animal data

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