Selection of Working Correlation Structure in Weighted Generalized Estimating Equation Method for Incomplete Longitudinal Data

摘要

The weighted generalized estimating equation (WGEE), an extension of the generalized estimating equation (GEE) method, is a method for analyzing incomplete longitudinal data. An inappropriate specification of the working correlation structure results in the loss of efficiency of the GEE estimation. In this study, we evaluated the efficiency of WGEE estimation for incomplete longitudinal data when the working correlation structure was misspecified. As a result, we found that the efficiency of the WGEE estimation was lower when an improper working correlation structure was selected, similar to the case of the GEE method. Furthermore, we modified the criterion proposed by Gosho et al. (2011) for selecting a working correlation structure, such that the GEE and WGEE methods can be applied to incomplete longitudinal data, and we investigated the performance of the modified criterion. The results revealed that when the modified criterion was adopted, the proportion that the true correlation structure was selected was likely higher than that in the case of adopting other competing approaches.