Tacrolimus versus cyclosporin for immunosuppression in renal transplantation: meta-analysis of randomised trials

摘要

Objective To compare tacrolimus with cyclosporin for immunosuppression in renal transplantation. Design Meta-analysis of randomised trials of two Treatments after kidney transplantation. Identification Four studies involving 1037 patients. Trials were included if they were randomised, The intervention group received tacrolimus, the Control group received cyclosporin, the patients Were followed for a minimum of 12 months, and Patient survival, graft survival, incidence of acute Rejection, need for antilymphocyte treatment, or the Prevalence of diabetes mellitus after transpolant was Reported.