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Two acetylated megastigmane glycosides from the leaves of Ilex paraguariensis

机译:巴拉圭冬青叶中的两种乙酰化大头翁配糖苷

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摘要

Two acetylated megastigmane glycosides, matenosides A (1) and B (2), have been isolated from the MeOH extract of Ilex paraguariensis leaves, and their structures were elucidated on the basis of spectroscopic analysis. Compounds 1 and 2 exhibited human neutrophil elastase (HNE) inhibitory activity with IC50 values of 50.4 μM and 11.1 μM, respectively.
机译:从乙酰巴拉圭冬青树叶的MeOH提取物中分离了两种乙酰化的大麦苷,糖苷A(1)和B(2),并在光谱分析的基础上阐明了它们的结构。化合物1和2表现出人类嗜中性粒细胞弹性蛋白酶(HNE)抑制活性,IC 50 值分别为50.4μM和11.1μM。

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