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MEGASTIGMANE DERIVATIVES ISOLATED FROM ILEX PARAGUARIENSIS, PREPARATION METHOD THEREOF AND ANTI-WRINKLE COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT
MEGASTIGMANE DERIVATIVES ISOLATED FROM ILEX PARAGUARIENSIS, PREPARATION METHOD THEREOF AND ANTI-WRINKLE COMPOSITION CONTAINING THE SAME AS AN ACTIVE INGREDIENT
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机译:一种从伊莱克斯伞菌中分离得到的美加士丹烷衍生物,其制备方法和包含活性成分相同的抗皱成分
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摘要
PURPOSE: A novel megastigmane derivative or pharmaceutically acceptable salt thereof is provided to prevent or treat wrinkling. CONSTITUTION: A megastigmane derivative or pharmaceutically acceptable salt thereof is denoted by chemical formula 1 or 2. A method for preparing the megastigmane derivative comprises: a step of adding water, organic solvent, or mixture solvent thereof to Ilex paraguariensis to prepare Ilex paraguariensis extract; a step of fractioning the Ilex paraguariensis extract with n-hexane and ethyl acetate to prepare an Ilex paraguariensis fraction; and a step of performing column chromatography.
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