Selective M1 macrophage polarization in granuloma-positive and granuloma-negative Crohns disease in comparison to intestinal tuberculosis

摘要

Background/AimsClassical M1 macrophage activation exhibits an inflammatory phenotype while alternative M2 macrophage activation exhibits an anti-inflammatory phenotype. We aimed to determine whether there are discriminant patterns of macrophage polarization in Crohn's disease (CD) and intestinal tuberculosis (iTB).