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Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation

机译：淀粉样蛋白β二聚体/三聚体有效诱导cofilin-actin棒通过维持cofilin磷酸化来抑制

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BackgroundPreviously we reported 1 μM synthetic human amyloid beta1-42 oligomers induced cofilin dephosphorylation (activation) and formation of cofilin-actin rods within rat hippocampal neurons primarily localized to the dentate gyrus.

机译：背景以前我们报道了1μM合成人淀粉样蛋白β1-42寡聚体诱导大鼠海马神经元内主要定位于齿状回的cofilin去磷酸化（激活）和cofilin-actin棒的形成。

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期刊名称 Molecular Neurodegeneration
作者
Richard C Davis; Ian T Marsden; Michael T Maloney; Laurie S Minamide; Marcia Podlisny; Dennis J Selkoe; James R Bamburg;
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年(卷),期 2011(6),-1
年度 2011
页码 10
总页数 17
原文格式 PDF
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中图分类神经科学;
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专利

1. Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation [J] . Richard C Davis, Ian T Marsden, Michael T Maloney, Molecular neurodegeneration . 2011,第1期

机译：淀粉样蛋白β二聚体/三聚体有效诱导cofilin-actin棒，通过维持cofilin-磷酸化来抑制
2. Mapping cofilin-actin rods in stressed hippocampal slices and the role of cdc42 in amyloid-beta-induced rods. [J] . Davis RC, Maloney MT, Minamide LS Journal of Alzheimer's disease: JAD . 2009,第1期

机译：在应激的海马切片中绘制cofilin-actin杆以及在淀粉样β诱导的杆中cdc42的作用。
3. Cellular prion protein: A co-receptor mediating neuronal cofilin-actin rod formation induced by beta-amyloid and proinflammatory cytokines [J] . Walsh Keifer P., Kuhn Thomas B., Bamburg James R. Prion . 2014,第6期

机译：细胞病毒蛋白：介导β-淀粉样蛋白和促炎性细胞因子诱导的神经元cofilin-actin棒形成的共受体
4. Pituitary adenylate cyclase-activating polypeptide inhibited the beta-amyloid-induced neurotoxicity and activation of caspase-3 [C] . Kosuke Endo, Satomi Onoue, Keiichi Ohshima, European Peptide Symposium . 2002

机译：垂体腺苷酸环酶活化多肽抑制β-淀粉样蛋白诱导的神经毒性和Caspase-3的活化
5. The study of amyloid beta (Abeta) induced ADF/cofilin rods in cultured neurons: Implications in Alzheimer's disease and neurodegeneration. [D] . Maloney, Michael T. 2006

机译：淀粉样β（Abeta）诱导培养的神经元中ADF / cofilin棒的研究：对阿尔茨海默氏病和神经变性的影响。
6. Mapping Cofilin-Actin Rods in Stressed Hippocampal Slices and the Role of cdc42 in Amyloid-β-Induced Rods [O] . Richard C. Davis, Michael T. Maloney, Laurie S. Minamide, -1

机译：应激海马切片中Cofilin-Actin杆的定位及cdc42在淀粉样β诱导杆中的作用
7. Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation [O] . Richard C Davis, Ian T Marsden, Michael T Maloney, 2011

机译：淀粉样蛋白β二聚体/三聚体有效诱导cofilin-actin棒，通过维持cofilin磷酸化来抑制

Amyloid beta dimers/trimers potently induce cofilin-actin rods that are inhibited by maintaining cofilin-phosphorylation

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