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Effectiveness of 7.5 Percent Povidone Iodine in Comparison to 1 Percent Clotrimazole with Lignocaine in the Treatment of Otomycosis

机译:7.5%的聚维酮碘与1%的克霉唑和利多卡因相比在治疗渗透性皮肤病中的有效性

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摘要

Objectives. Otomycosis is a common ENT disease frequenting the tropics. Its recurrent nature poses a great challenge to the treating physician. In spite of a number of antifungals in the market, the frequent nature of this disease warrants repeated use of these drugs, contributing to drug resistance and financial burden on the rural population. Our primary aims were to evaluate the effectiveness of povidone iodine in the treatment of otomycosis and to identify the most common fungal isolate in our population. Study Design and Setting. A single blinded prospective longitudinal study was done over a period of 12 months in a tertiary referral center. 34 patients in the age group 15–70 years clinically diagnosed with otomycosis were included in this study. These individuals were divided into two groups selected randomly. One arm received 7.5% povidone iodine otic drops and the other 1% Clotrimazole and lignocaine drops. Evaluation was based on resolution of symptoms and signs after treatment. Result. Both arms showed improvements which were comparable thus suggesting the role of povidone iodine in the management of otomycosis. Conclusion. Povidone iodine is an effective antifungal in the treatment of otomycosis.
机译:目标。牙菌病是热带地区常见的耳鼻喉科疾病。它的复发性质对治疗医师提出了巨大挑战。尽管市场上有许多抗真菌药,但这种疾病的频发性质仍需要重复使用这些药物,这导致了耐药性和农村人口的经济负担。我们的主要目的是评估聚维酮碘在治疗真菌病中的功效,并确定我们人群中最常见的真菌分离株。研究设计和设置。在三级转诊中心进行了为期12个月的单盲前瞻性纵向研究。本研究包括临床诊断为耳菌病的年龄在15-70岁之间的34位患者。将这些人分为随机选择的两组。一只手臂接受了7.5%聚维酮碘滴眼液,另一只接受了1%克霉唑和利多卡因滴眼液。评估基于治疗后症状和体征的缓解。结果。双臂均表现出可比的改善,从而表明聚维酮碘在耳菌病治疗中的作用。结论。聚维酮碘是治疗真菌病的有效抗真菌药。

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