Effects of Seasonal Changes on the Patients Flux to Basic Health Units in Pakistan

摘要

Immune response in humans, along with animals, is dependent on seasonal changes. Children’s humoral and cell mediated immune response decreases in rainy season especially in tropical areas while in temperate zones decreased resistance against influenza is observed in winter (1). Immune response was more pronounced and more active during winter season. Melatonin, a key factor to enhance activity of immune system, is more in winter season. Length of the day triggers immune system activation (2). When the day light shortens it triggers glucocorticosteroid hormones especially adreno-corticosteroidal hormone. Consequently, boosting immunity in individuals. Lymphatic system changes can be observed by changed lymph organ sizes and structures which are high in the beginning of winter season or in late autumn. Human species in particular and all other species in general show these changes (3, 4). Result of environmental changes cause outbreak of disease in the region of the same latitude (5).