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Repurposing Ferumoxytol as a Breast Cancer-Associated Macrophage Tracer with Five-Dimensional Quantitative FeMRI of SPION Dynamics

机译：用五维定量Fe MRI的乳腺癌相关的巨噬细胞示踪剂将FEROMOXYTOL作为乳腺癌相关的巨噬细胞示踪剂进行修复

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期刊名称 Cancers
作者
Laurel O. Sillerud; Alexander J. Neuwelt; Fernanda I. Staquicini; Wadih Arap; Renata Pasqualini;
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作者单位

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年(卷),期 2021(13),15
年度 2021
页码 3802
总页数 16
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

机译：ferumoxytol;三阴性乳腺癌;MRI;FE MRI;

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专利

1. In vivo quantitative detection of tumour associated macrophages (TAM) in mice melanoma models, by relaxation measurements (T1) at low magnetic fields with Ferumoxytol [J] . S.Geninatti Crich, M.R.Ruggiero, S.Baroni, Magma: Magnetic resonance materials in physics, biology, and medicine . 2019,第1Suppla1期

机译：在小鼠黑色素瘤模型中的肿瘤相关巨噬细胞（TAM）的体内定量检测，通过Ferumoxytol的低磁场下的弛豫测量（T1）
2. Polyethylenimine-coated SPIONs trigger macrophage activation through TLR-4 signaling and ROS production and modulate podosome dynamics [J] . Mulens-Arias Vladimir, Rojas Jose M., Perez-Yaguee Sonia, Biomaterials . 2015,第Null期

机译：聚乙烯亚胺涂层的SPIONs通过TLR-4信号和ROS产生触发巨噬细胞活化并调节足小体动力学
3. Circulating Cancer-Associated Macrophage-Like Cells Differentiate Malignant Breast Cancer and Benign Breast Conditions [J] . Adams Daniel L., Adams Diane K., Alpaugh R. Katherine, Cancer epidemiology, biomarkers and prevention: A publication of the American Association for Cancer Research . 2016,第7期

机译：循环相关的巨噬细胞样细胞区分恶性乳腺癌和良性乳腺癌
4. Breast lesion dynamic radiotracer uptake quantification method utilizing a combined digital X-ray/gamma system [C] . Kieper, D., Green, . 2003

机译：利用组合数字X射线/γ系统的乳腺病变动态放射性示踪剂摄取量化方法
5. Quantitative FeMRI Determination of the Dynamics of PSMA-Targeted SPIONs Discriminates Among Prostate Tumor Xenografts Based on Their PSMA Expression [O] . Laurel O. Sillerud -1

机译：前列腺癌异种移植物中基于PSMA表达的PSMA靶向SPION动力学的定量Fe MRI测定
6. Quantitative FeMRI of PSMA-targeted SPIONs specifically discriminates among prostate tumor cell types based on their PSMA expression levels [O] . Laurel Sillerud 2016

机译：PSMA靶向孢子的定量Fe MRI在基于其PSMA表达水平的基于前列腺肿瘤细胞类型中具体判断

Repurposing Ferumoxytol as a Breast Cancer-Associated Macrophage Tracer with Five-Dimensional Quantitative FeMRI of SPION Dynamics

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