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LncRNA-SNHG7 Enhances Chemotherapy Resistance and Cell Viability of Breast Cancer Cells by Regulating miR-186

机译：通过调节miR-186LNCRNA-SNHG7增强乳腺癌细胞的化疗抗性和细胞活力

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摘要

Clinical tolerance to trastuzumab greatly affects the therapeutic effect in breast cancer (BC). Long-chain non-coding RNA (lncRNA) plays an important role in the development of trastuzumab resistance, in which SNHG7 can promote the epithelial mesenchymal transformation (EMT) of breast cancer cells into, while EMT is related to trastuzumab resistance of breast cancer cells.

机译：对曲妥珠单抗的临床耐受性大大影响了乳腺癌（BC）的治疗效果。长链非编码RNA（LNCRNA）在曲据的抗性发展中起重要作用，其中SNHG7可以促进乳腺癌细胞的上皮间度转化（EMT），而EMT与乳腺癌细胞的曲妥珠单抗抵抗力有关。

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期刊名称 Cancer Management and Research
作者
Hui Zhang; Xiao-Yu Zhang; Xiao-Ning Kang; Li-Jun Jin; Zun-Yi Wang;
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作者单位

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年(卷),期 2020(-1),-1
年度 2020
页码 -1
总页数 10
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词

机译：snhg7;mir-186;乳腺癌;耐药性;

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专利

1. LncRNA-SNHG7 Enhances Chemotherapy Resistance and Cell Viability of Breast Cancer Cells by Regulating miR-186 [J] . Hui Zhang, Xiao-Yu Zhang, Xiao-Ning Kang, Cancer Management and Research . 2020,第3期

机译：通过调节miR-186，LNCRNA-SNHG7增强乳腺癌细胞的化疗抗性和细胞活力
2. Radioresistant breast cancer cells exhibit increased resistance to chemotherapy and enhanced invasive properties due to cancer stem cells [J] . Ko Young Shin, Jin Hana, Lee Jong Sil, Oncology reports . 2018,第6期

机译：放射性乳腺癌细胞表现出对化疗的抗性增加，并且由于癌症干细胞增强的侵袭性
3. Enhanced efficacy of chemotherapy for breast cancer stem cells by simultaneous suppression of multidrug resistance and antiapoptotic cellular defense [J] . Sun Ming, Yang Chuanxu, Zheng Jin, Acta biomaterialia . 2015,第Null期

机译：通过同时抑制多药耐药性和抗凋亡细胞防御作用增强乳腺癌干细胞化学疗法的功效
4. Enhancing Chemotherapy by Ultrasound and Microbubbles: Effect of Acoustic Pressure and Treatment Order in In Vitro Suspension of Breast and Prostate Cancer Cells [C] . Raffi Karshafian, Firas Almasri, Anoja Giles, IEEE International Ultrasonics Symposium . 2010

机译：通过超声波和微泡增强化疗：声压和治疗顺序在体外悬浮液中乳腺癌和前列腺癌细胞的影响
5. The Influence of Stress Hormones on Breast Cancer Stem Cell Survival and Chemotherapy Resistance [D] . Courtney, Angela 2015

机译：应激激素对乳腺癌干细胞存活和化疗耐药性的影响
6. Silencing CDR1as enhances the sensitivity of breast cancer cells to drug resistance by acting as a miR‐7 sponge to down‐regulate REGγ [O] . Wei Yang, Xiaojuan Yang, Xuedong Wang, 2019

机译：沉默CDR1as通过充当miR-7海绵来下调REGγ从而增强乳腺癌细胞对耐药性的敏感性
7. >LncRNA-SNHG7 Enhances Chemotherapy Resistance and Cell Viability of Breast Cancer Cells by Regulating miR-186 [O] . Hui Zhang, Xiao-Yu Zhang, Xiao-Ning Kang, 2020

机译：> LNCRNA-SNHG7通过调节miR-186来增强乳腺癌细胞的化疗耐药性和细胞活力。

LncRNA-SNHG7 Enhances Chemotherapy Resistance and Cell Viability of Breast Cancer Cells by Regulating miR-186

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