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The m6A methyltransferase METTL14 inhibits the proliferation migration and invasion of gastric cancer by regulating the PI3K/AKT/mTOR signaling pathway

机译：M6A甲基转移酶METT14通过调节PI3K / AKT / MTOR信号通路来抑制胃癌的增殖迁移和侵袭

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摘要

N6‐methyladenosine (m6A) modification may participate in the regulation of occurrence and development of tumors. However, the m6A level and the potential regulatory mechanism of m6A in gastric cancer (GC) remain uncertain.

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期刊名称 Journal of Clinical Laboratory Analysis
作者
Xin Liu; Mingyang Xiao; Liang Zhang; Liuli Li; Guolian Zhu; Erdong Shen; Mingyue Lv; Xiaobo Lu; Zhe Sun;
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作者单位

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年(卷),期 2021(35),3
年度 2021
页码 e23655
总页数 10
原文格式 PDF
正文语种
中图分类生理学;
关键词
gastric cancer; methyltransferase‐like 14; prognosis; RNA m6A modification; tumor suppressor;

机译：胃癌;甲基转移酶样14;预后;RNA M6A修饰;肿瘤抑制器;

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专利

1. The m6A methyltransferase METTL14 inhibits the proliferation, migration, and invasion of gastric cancer by regulating the PI3K/AKT/mTOR signaling pathway [J] . Xin Liu, Mingyang Xiao, Liang Zhang, Journal of clinical laboratory analysis. . 2021,第3期

机译：M6A甲基转移酶METT14通过调节PI3K / AKT / MTOR信号通路来抑制胃癌的增殖，迁移和侵袭
2. miR-196b regulates gastric cancer cell proliferation and invasion via PI3K/AKT/mTOR signaling pathway [J] . Li Na, Wang Weiqiang, Xu Bin, Oncology letters . 2016,第3aPta2期

机译：miR-196b通过PI3K / AKT / mTOR信号通路调节胃癌细胞的增殖和侵袭
3. miR-196b regulates gastric cancer cell proliferation and invasion via PI3K/AKT/mTOR signaling pathway [J] . Li Na, Wang Weiqiang, Xu Bin, Oncology letters . 2016,第3aPta1期

机译：MIR-196B通过PI3K / AKT / MTOR信号通路调节胃癌细胞增殖和侵袭
4. Label-free phosphoproteomics method to investigate signaling pathways downstream of novel PI3K/mTOR inhibitors in cancer cells [C] . Pedro Casado, Juan Carlos Rodriguez-Prados, Sabina Cosulich, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2011

机译：无标记的磷蛋白质方法，用于研究新型PI3K / MTOR抑制剂在癌细胞中的信号通路
5. The multi-targeted receptor tyrosine kinase inhibitor, linifanib (ABT-869), induces apoptosis and inhibits proliferation of leukemia cells through phosphoinositide-3 kinase (PI3K)/AKT-dependent signaling pathways. [D] . Hernandez, Jenny Elizabeth. 2010

机译：多靶点受体酪氨酸激酶抑制剂利尼法尼（ABT-869）通过磷酸肌醇3激酶（PI3K）/ AKT依赖性信号传导途径诱导凋亡并抑制白血病细胞的增殖。
6. Long noncoding RNA STXBP5-AS1 inhibits cell proliferation migration and invasion through inhibiting the PI3K/AKT signaling pathway in gastric cancer cells [O] . Dongzhi Cen, Hu Huang, Liu Yang, 2019

机译：长非编码RNA STXBP5-AS1通过抑制胃癌细胞中的PI3K / AKT信号传导途径抑制细胞增殖迁移和侵袭
7. Retracted : Knockdown of SRPX2 inhibits the proliferation, migration, and invasion of prostate cancer cells through the PI3K/Akt/mTOR signaling pathway [O] . 2018

机译：缩回：SRPX2的敲低通过PI3K / AKT / MTOR信号传导途径抑制前列腺癌细胞的增殖，迁移和侵袭

The m6A methyltransferase METTL14 inhibits the proliferation migration and invasion of gastric cancer by regulating the PI3K/AKT/mTOR signaling pathway

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