Reticulocytosis As a Whistleblower: A Rare Case of Acquired Elliptocytosis in a Myelodysplastic Syndrome Patient With Trisomy 8

摘要

Elliptocytosis is a corpuscular erythrocyte abnormality characterized by the presence of oval or elliptical erythrocytes on the blood smear. In most cases, it is an inherited condition, but a few cases of acquired elliptocytosis (AE) have been described in myeloid malignancies, most often in myelodysplastic syndrome (MDS) associated with del(20q).1 This report describes the first case of AE in a patient presenting with regenerative anemia and dysgranulopoiesis leading to the diagnosis of MDS with isolated trisomy 8. AE was associated with rapid transformation in our patient, which will be discussed in light of the data from the literature.