首页> 外国专利> methods of treating, preventing or controlling a myelodysplastic syndrome, reducing or preventing an adverse effect associated with the administration of a second active ingredient in a patient suffering from a myelodysplastic syndrome, pharmaceutical composition, single unit dosage form, and kit

methods of treating, preventing or controlling a myelodysplastic syndrome, reducing or preventing an adverse effect associated with the administration of a second active ingredient in a patient suffering from a myelodysplastic syndrome, pharmaceutical composition, single unit dosage form, and kit

机译:在患有骨髓增生异常综合症的患者中治疗,预防或控制骨髓增生异常综合症,减少或预防与施用第二种活性成分相关的不良反应的方法,药物组合物,单一单位剂型和试剂盒

摘要

METHODS OF TREATMENT, PREVENTION OR CONTROL OF A MYELODISPLASTIC SYNDROME, REDUCTION OR AVOIDANCE OF AN ADVERSE EFFECT ASSOCIATED WITH ADMINISTRATION OF AN ACTIVE INGREDIENT SECOND, PATIENT UNIFIED SYNDROME, SYNDROME Methods of treatment, prevention, and / or control of myelodysplastic syndrome are described. Specific methods include administering a pharmaceutically acceptable cytokine inhibitor drug, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate or prodrug thereof, alone or in combination with a second active ingredient, and / or blood or cells for therapy. transplantation. The second specific active compounds are capable of affecting or improving blood cell production. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also described.
机译:介绍了一种治疗,预防或控制骨髓增生异常综合征,减少或避免伴有积极成分的第二,患者统一统一综合征,综合症的不良反应的治疗,预防和/或控制骨髓增生异常综合征的方法。具体方法包括单独或与第二活性成分组合施用药学上可接受的细胞因子抑制剂药物或其药学上可接受的盐,溶剂化物,水合物,立体异构体,包合物或前药,和/或血液或细胞进行治疗。移植。第二种特定的活性化合物能够影响或改善血细胞的产生。还描述了适用于本发明方法的药物组合物,单一单位剂型和试剂盒。

著录项

  • 公开/公告号BRPI0418743A

    专利类型

  • 公开/公告日2007-09-18

    原文格式PDF

  • 申请/专利权人 CELGENE CORPORATION;

    申请/专利号BR2004PI18743

  • 发明设计人 JEROME B. ZELDIS;

    申请日2004-04-14

  • 分类号A61K31/425;A01N43/38;A61K45/06;

  • 国家 BR

  • 入库时间 2022-08-21 20:59:24

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