首页> 外国专利> methods of treating, preventing or controlling a myelodysplastic syndrome, reducing or preventing an adverse effect associated with the administration of a second active ingredient in a patient suffering from a myelodysplastic syndrome, pharmaceutical composition, single unit dosage form, and kit

methods of treating, preventing or controlling a myelodysplastic syndrome, reducing or preventing an adverse effect associated with the administration of a second active ingredient in a patient suffering from a myelodysplastic syndrome, pharmaceutical composition, single unit dosage form, and kit

机译:在患有骨髓增生异常综合症的患者中治疗,预防或控制骨髓增生异常综合症,减少或预防与施用第二种活性成分相关的不良反应的方法,药物组合物,单一单位剂型和试剂盒

摘要

"METHODS OF TREATMENT, PREVENTION OR CONTROL OF A MYELODISPLASTIC SYNDROME, REDUCING OR AVOIDING AN ADVERSE EFFECT ASSOCIATED WITH ADMINISTRATION OF AN ACTIVE INGREDIENT SYNDROME, PATIENT UNIFIED SYNDROME, PATIENTS Methods of treatment, prevention, and / or control of myelodysplastic syndromes are described. Specific methods include administering an immunomodulatory compound, or a pharmaceutically acceptable salt, solvate, hydrate, stereoisomer, clathrate or prodrug thereof, alone or in combination with a second active ingredient, and / or transplanting blood or cells. . The second specific active compounds are capable of affecting blood cell production. Pharmaceutical compositions, single unit dosage forms, and kits suitable for use in methods of the invention are also described.
机译:“治疗,预防或控制骨髓增生异常综合征的方法,减少或避免伴随主动性原发性综合征,患者统一的综合征,患者的不良反应的治疗,预防和/或控制骨髓增生异常综合征的方法。方法包括单独或与第二活性成分组合施用免疫调节化合物或其药学上可接受的盐,溶剂化物,水合物,立体异构体,包合物或前药,和/或移植血液或细胞。还描述了适用于本发明方法的药物组合物,单一单位剂型和试剂盒。

著录项

  • 公开/公告号BRPI0418742A

    专利类型

  • 公开/公告日2007-09-11

    原文格式PDF

  • 申请/专利权人 CELGENE CORPORATION;

    申请/专利号BR2004PI18742

  • 发明设计人 JEROME B. ZELDIS;

    申请日2004-04-14

  • 分类号A61K31/445;A61K35/28;A61K35/50;A61K35/51;A61K38/16;A61K38/18;A61K38/19;A61K38/20;A61K45/06;C07D401/04;C07K14/435;C07K14/52;C07K14/53;C07K14/54;C07K14/55;

  • 国家 BR

  • 入库时间 2022-08-21 20:59:24

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