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Fusion Surgery for Lumbar Spinal Stenosis: WFNS Spine Committee Recommendations

机译:腰椎管狭窄融合手术:WFNS脊柱委员会建议

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摘要

Lumbar spine stenosis represents a complex degenerative pathology that has been a subject of significant dispute when it comes to fusion. A review of the literature from 2008 to 2019 was performed on the role of fusion in the treatment of lumbar spinal stenosis using PubMed, Ovid Medline, Cochrane Central Register of Controlled Trials, and the Cochrane Database of Systematic Reviews. Using the key words “lumbar spinal stenosis,” “lumbar fusion,” “lumbar decompression,” and “lumbar pedicle screw fixation,” the search revealed 490 papers. Of these, only Level 1 or Level 2 evidence papers were selected, leading to only 3 randomized controlled trials (RCTs) that were analyzed. None of the good-quality studies (RCTs) performed so far have proven any clinical benefit of adding fusion to degenerative lumbar spine decompression. The effect of spinal instability on the outcome following decompression remains controversial. At present, no unanimous criteria exist among the RCTs to identify what constitutes true instability. Fusion for instability or stenosis alone remains controversial, and the results are unconvincing. At this point, the issue expands to not only lumbar degenerative diseases but spinal fractures and lumbar isthmic spondylolisthesis. We thereby present the consensus of the World Federation of Neurosurgical Societies Spine Committee, which formulated the indications for lumbar spine fusion in degenerative lumbar stenosis.
机译:腰椎管狭窄症是一种复杂的退行性病变,融合时一直是一个重大争议的话题。使用PubMed,Ovid Medline,对照试验的Cochrane中央注册系统和Cochrane系统评价数据库,对2008年至2019年的融合在腰椎管狭窄症治疗中的作用进行了文献综述。搜索使用关键词“腰椎管狭窄”,“腰椎融合术”,“腰椎减压术”和“腰椎椎弓根螺钉固定术”,共检索到490篇论文。其中,仅选择了1级或2级证据文件,因此仅分析了3项随机对照试验(RCT)。到目前为止,尚无一项优质研究(RCT)证明在融合性腰椎减压术中增加融合有任何临床益处。减压后脊柱不稳对预后的影响尚存争议。目前,在RCT中尚无一致的标准来确定什么构成真正的不稳定。仅针对不稳定或狭窄的融合仍存在争议,其结果令人信服。在这一点上,这个问题不仅扩展到腰椎退行性疾病,还扩展到脊柱骨折和腰椎峡部峡部滑脱。因此,我们提出了世界神经外科学会联合会脊柱委员会的共识,该委员会制定了退行性腰椎管狭窄症中腰椎融合的适应症。

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