Low-Dose of β-Hydroxy-β-Methylbutyrate (HMB) Alleviates Muscle Strength Loss and Limited Joint Flexibility Following Eccentric Contractions

摘要

The excessive exercise including eccentric contractions (ECCs) cause the reduction of maximal strength, limitation of range of motion (ROM), developed muscle soreness, and muscle swelling for several days from immediately after exercise. Therefore, it is important to promote the recovery of muscle damage and minimize decreases in muscle function and muscle soreness after exercise. We recently examined the effects of 2- and 4-week β-hydroxy-β-methylbutyrate (HMB) supplementation (3 g/day) on ECCs-induced muscle damage. As the result, both the 2- and 4-week treatments decreased muscle strength reduction, ROM, and muscle swelling. However, the optimal dose of HMB required for decreasing muscle damage remains unknown. Therefore, this study investigated the supplemental effect of low-dose HMB on muscle damage after ECCs of human elbow flexor muscles.