Pien Tze Huang alleviate the joint inflammation in collagen-induced arthritis mice

摘要

PZH ameliorated the symptoms of CIA mice. Mice were orally administered with PZH-L (0.078 g/kg/day), PZH-M (0.234 g/kg/day), PZH-H (0.702 g/kg/day), MTX (0.3 mg/kg/day) or pure water (both Normal group and Model group) for 28 days. Representative photograph of ankle joint from each group. Arthritis score of each group. Representative pathological sections of the ankle joint by H&E staining (×200, scale bars = 100 μm). The black arrow indicates the inflammatory site. Histology score of each group. n = 6 each group. P