The mir-767-105 cluster: a crucial factor related to the poor prognosis of hepatocellular carcinoma

摘要

legend. TCGA database exploration of mir-767-105 cluster in hepatocellular carcinoma (HCC). Top 10 mirna expression levels in HCC. The top 1–3 belonged to mir-767-105 cluster. Comprehensive comparison of the mir-767-105 cluster expression levels between the HCC samples and non-tumour samples. Error bars represented the mean ± SEM. ****represent a -value P-value was calculated with the Mann-Whitney test. Heatmap of mir-767-105 expression levels from 50 non-tumour samples and 373 HCC samples. Kaplan-Meier survival analysis with log-rank test between the low and high expression of the mir-767(left), mir-105-1(middle), and mir-105a-2(right) expression levels was performed. The results of univariate Cox analysis was shown with the forest plot, and the multivariate Cox analysis was shown as Table. The items from Gene Ontology in biological process, cellular component and molecular function. The top 20 items from Kyoto Encyclopedia of Genes and Genomes