COMPOSITION FOR DIAGNOSIS OF HEPATOCELLULAR CARCINOMAS COMPRISING TM7SF3, AND DIAGNOSIS KIT OF HEPATOCELLULAR CARCINOMAS AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING HEPATOCELLULAR CARCINOMAS COMPRISING ANTI TM7SF3 ANTIBODY

摘要

PURPOSE: A TM7SF3 which is useful as a marker for diagnosing liver cancer is provided to highly and specifically express in a tissue of a patient with liver cancer and to predict and diagnose liver cancer. CONSTITUTION: A composition for diagnosing liver cancer contains TM7SF3 as an active ingredient. A kit for diagnosing liver cancer contains an anti-TM7SF3 antibody as an active ingredient. The antibody is an antibody which specifically binds to extracellular domain of TM7SF3 encoded by a base sequence of sequence number 3. The TM7SF3 detection in the liver tissue is performed by antibody-antigen bond using the TM7SF3-specfiic antibody. The TM7SF3 is highly expressed in liver cancer tissue. A pharmaceutical composition for preventing or treating contains the anti-TM7SF3 antibody as an active ingredient. The antibody is monoclonal antibody or polyclonal antibody.