Interplay between Neuroendocrine Biomarkers and Gut Microbiota in Dogs Supplemented with Grape Proanthocyanidins: Results of Dietary Intervention Study

摘要

The connection between animal health and gut microbiota has been studied during the past years through different diet modulation experiments; however, there is still a paucity of information about the prebiotic functions in the gastrointestinal tract of companion animals. Considering this, a population of dogs living in the same environment has been subjected to a nutritional study, with different doses of proanthocyanidins extracted from grapevine supplied to the diet. Characterization of the gut microbiota and data from endocrine analysis in saliva have been collected. Dogs responded differently to the dietary intervention, and results underlined the existence of a difference between subjects in terms of fecal microorganisms and neuroendocrine markers, leading us to think the balance of gut microbiota is going to play a strong role in diet formulation based on host health modulation.