Diastereoselective Synthesis of Cyclopenta-pyridazinones via Radical Cyclization

摘要

The pyridazinone ring system serves as an excellent scaffold for the diastereoselective preparation of novel cis-fused cyclopenta-pyridazinones utilizing the directed 5-exo radical cyclization approach. This overall approach was successfully employed in the preparation of a functionalized aza-spirocycle.