Prediction of cardioembolic arterial and lacunar causes of cryptogenic stroke by gene expression and infarct location

摘要

Background and PurposeThe cause of ischemic stroke remains unclear, or cryptogenic, in as many as 35% of stroke patients. Not knowing the cause of stroke restricts optimal implementation of prevention therapy and limits stroke research. We demonstrate how gene expression profiles in blood can be used in conjunction with a measure of infarct location on neuroimaging to predict a probable cause in cryptogenic stroke.