IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways

机译：IMPDH2通过激活PI3K / AKT / mTOR和PI3K / AKT / FOXO1信号通路促进大肠癌的进展

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BackgroundInosine 5′-monophosphate dehydrogenase type II (IMPDH2) was originally identified as an oncogene in several human cancers. However, the clinical significance and biological role of IMPDH2 remain poorly understood in colorectal cancer (CRC).

机译：背景II型肌苷5'-单磷酸脱氢酶（IMPDH2）最初被确定为几种人类癌症的致癌基因。然而，IMPDH2的临床意义和生物学作用在大肠癌（CRC）中仍然知之甚少。

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期刊名称 Journal of Experimental Clinical Cancer Research : CR
作者
Shiyu Duan; Wenqing Huang; Xiaoting Liu; Xuming Liu; Nana Chen; Qiong Xu; Yukun Hu; Wen Song; Jun Zhou;
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作者单位

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年(卷),期 2018(37),-1
年度 2018
页码 304
总页数 16
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
IMPDH2 Colorectal cancer Proliferation Cell cycle EMT;

机译：IMPDH2;结直肠癌;增殖;细胞周期;EMT;

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专利

1. IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways [J] . Shiyu Duan, Wenqing Huang, Xiaoting Liu, Journal of experimental & clinical cancer research : . 2018,第1期

机译：IMPDH2通过激活PI3K / AKT / mTOR和PI3K / AKT / FOXO1信号通路促进大肠癌的进展
2. Anthrax toxin receptor 1/tumor endothelial marker 8 promotes gastric cancer progression through activation of the PI3K/AKT/mTOR signaling pathway [J] . Chen Cai, Wei Dang, Shilei Liu, Cancer science. . 2020,第4期

机译：炭疽毒素受体1 /肿瘤内皮标记物8通过激活PI3K / AKT / MTOR信号通路促进胃癌进展
3. FOXK1 promotes malignant progression of breast cancer by activating PI3K/AKT/mTOR signaling pathway [J] . Z.-Q. Li, M. Qu, H.-X. Wan, European review for medical and pharmacological sciences. . 2019,第22期

机译：FOXK1通过激活PI3K / AKT / mTOR信号通路促进乳腺癌的恶性进展
4. Ang-2 promoting proliferation of SW1116 colon cancer cells through PI3K/Akt pathways [C] . Hong Zhang Ji, Yang Wen Chun, Ping Wang Ai, 2011 International Conference on Human Health and Biomedical Engineering . 2011

机译：Ang-2通过PI3K / Akt途径促进SW1116结肠癌细胞的增殖
5. Sensitivity of MCF-7 breast cancer cells to anticancer drugs is decreased by activation of the PI3K/PDK/Akt signal transduction pathway. [D] . Navolanic, Patrick M. 2004

机译：通过激活PI3K / PDK / Akt信号转导途径，MCF-7乳腺癌细胞对抗癌药物的敏感性降低。
6. Anthrax toxin receptor 1/tumor endothelial marker 8 promotes gastric cancer progression through activation of the PI3K/AKT/mTOR signaling pathway [O] . Chen Cai, Wei Dang, Shilei Liu, 2020

机译：炭疽毒素受体1 /肿瘤内皮标记物8通过激活PI3K / AKT / mTOR信号通路促进胃癌的进展
7. IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways [O] . Shiyu Duan, Wenqing Huang, Xiaoting Liu, 2018

机译：IMPH2通过激活PI3K / AKT / MTOR和PI3K / AKT / FOXO1信号通路来促进结肠直肠癌进展

IMPDH2 promotes colorectal cancer progression through activation of the PI3K/AKT/mTOR and PI3K/AKT/FOXO1 signaling pathways

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