E2F8 a direct target of miR-144 promotes papillary thyroid cancer progression via regulating cell cycle

摘要

BackgroundThyroid cancer is the most common malignancy of endocrine system, and papillary thyroid cancer (PTC) is the most common subtype. E2F8, a novel identified E2F family member, was reported to associate with progression of several human cancers, however, its clinical significance and biological role in PTC remain unknown.