Denatonium induces secretion of glucagon-like peptide-1 through activation of bitter taste receptor pathways

摘要

Aims/hypothesisThis study was designed to ascertain whether human enteroendocrine cells express bitter taste receptors, and whether activation of these receptors with bitter-tasting ligands induces secretion of glucagon-like peptide-1 (GLP-1) and peptide YY (PYY).