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Verification of a Defibrillation Simulation Using Internal Electric Fields in a Human Shaped Phantom

机译:使用人形幻象中的内部电场对除颤模拟进行验证

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摘要

We have developed a computer simulation to evaluate the success of Implantable Cardioverter Defibrillators (ICDs) in a patient specific manner. Though we have verified the simulations by means of surface recordings of shock potentials in humans, recordings of potentials within the heart and torso are needed to further verify the model for use in a clinical setting. We suspended an ex-planted porcine heart in a torso shaped electrolytic tank and recorded potentials on the tank surface, the epicardial surface, and within the myocardium during ICD shocks and compared these recordings to finite element solutions based on the same geometries. Potentials recorded from the surface and within the volume of the torso tank agreed well with the simulated potentials. Quantitative comparison between recorded and simulated potentials showed a mean correlation of 0.90, a mean normalized RMS error of 0.102, and a mean relative error of 26.5%. These results suggest that our simulation model can guide the optimization of ICD design and use.
机译:我们已经开发了一种计算机模拟程序,可以以患者特定的方式评估植入式心脏复律除颤器(ICD)的成功性。尽管我们已经通过对人类电击电位的表面记录进行了验证,但是仍需要记录心脏和躯干内部的电位,以进一步验证该模型是否可用于临床。我们在ICD休克期间将一个离体的猪心脏悬吊在一个躯干形的电解槽中,并记录了槽表面,心外膜表面以及心肌内的电位,并将这些记录与基于相同几何形状的有限元解决方案进行了比较。从躯干水箱的表面和内部记录的电势与模拟电势非常吻合。记录电势和模拟电势之间的定量比较显示,平均相关性为0.90,平均归一化RMS误差为0.102,平均相对误差为26.5%。这些结果表明,我们的仿真模型可以指导ICD设计和使用的优化。

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