Long Non-Coding RNA Expression Profile in the Kidneys of Male Low Birth Weight Rats Exposed to Maternal Protein Restriction at Postnatal Day 1 and Day 10

摘要

BackgroundLong non-coding RNAs (lncRNAs), which are involved in a variety of biological functions and aberrantly expressed in many types of diseases, are required for postnatal development. In this study, we aimed to investigate the lncRNA profiles in low birth weight (LBW) rats with reduced nephron endowment induced by the restriction of maternal protein intake. LBW by reduced nephron endowment is a risk factor for hypertension and end-stage renal disease in adulthood.