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Prevalence of Chlamydia trachomatis Genotypes in Men Who Have Sex with Men and Men Who Have Sex with Women Using Multilocus VNTR Analysis-ompA Typing in Guangzhou China

机译:多位点VNTR分析-ompA分型在中国广州市男男性接触者和男男性接触者中沙眼衣原体基因型的患病率

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摘要

BackgroundChlamydia trachomatis is one of the most prevalent bacterial sexually transmitted infection in China. Although C. trachomatis genotypes can be discriminated by outer membrane protein gene (ompA) sequencing, currently available methods have limited resolutions. This study used a high-resolution genotyping method, namely, multilocus variable number tandem-repeat analysis with ompA sequencing (MLVA)-ompA, to investigate the local epidemiology of C. trachomatis infections among men who have sex with men (MSM) and men who have sex with women (MSW) attending a sexually transmitted diseases (STD) clinic in Guangzhou, China.
机译:背景沙眼衣原体是中国最普遍的细菌性传播感染之一。尽管沙眼衣原体基因型可以通过外膜蛋白基因(ompA)测序来区分,但目前可用的方法分辨率有限。这项研究使用了高分辨率基因分型方法,即通过ompA测序(MLVA)-ompA进行多基因座可变数串联重复分析,以调查在男男性接触者(MSM)和男性中沙眼衣原体感染的局部流行病学在中国广州的性传播疾病(STD)诊所与女性发生性关系的女性。

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