Nickel-Catalyzed C-Alkylation of Nitroalkanes with Unactivated Alkyl Iodides

摘要

Enabled by nickel catalysis, a mild and general catalytic method for C-alkylation of nitroalkanes with unactivated alkyl iodides is described. Compatible with primary, secondary and tertiary alkyl iodides, and tolerant of a wide range functional groups, this method allows rapid access to diverse nitroalkanes.