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Age of Initiation and Substance Use Progression: A Multivariate Latent Growth Analysis

机译:起始年龄和物质使用进度:多元潜在增长分析

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摘要

An individual’s age at first substance use may be associated with their risk for progression toward heavier substance involvement. To our knowledge, however, no studies within nationally-representative samples have examined the relation between the timing of initiation and progression in use of multiple substances. The present study employed a sample of 9,421 participants from the National Longitudinal Study of Adolescent to Adult Health who reported on their ages of tobacco, alcohol, and cannabis initiation; frequency of tobacco, alcohol, and cannabis use; and quantity of tobacco and alcohol use across four waves. We fit latent growth models to examine (a) associations between the age of initiation and initial status and rate of change in substance involvement, and (b) the degree to which the timing of first substance use accounted for differences in trajectories. There were significant relations between all ages of initiation and rates of change in tobacco (βs=−0.21 to −0.31, ps<.01) and alcohol use frequency (βs=0.14 to 0.31, ps<.001), age of cannabis initiation and rate of change in tobacco use quantity (β=0.23, p<.01), and age of tobacco initiation and rate of change in cannabis use frequency (β= −0.14, p<.01). After adjusting for age of initiation, significant associations were observed between trajectories for tobacco and alcohol (r=0.43, p<.0001) and alcohol and cannabis (r=0.20, p<.05). Results highlight differences in within- and cross-substance relations between the age of initiation and rate of change in use across substances. They suggest that differences in substance use trajectories are partly accounted for by age at first use.
机译:初次使用毒品的人的年龄可能与其发展为重度毒品侵害的风险有关。据我们所知,没有国家代表样品中的研究检查过多种物质使用的起始时间和进展之间的关系。本研究采用了来自全国青少年健康成人纵向研究的9,421名参与者的样本,他们报告了其吸烟,酗酒和吸食大麻的年龄。烟草,酒精和大麻的使用频率;四波浪中的烟草和酒精使用量我们采用潜在增长模型来研究(a)起始年龄和初始状态与物质参与变化率之间的关联,以及(b)首次使用药物的时机解释轨迹差异的程度。烟草起始年龄与烟草起始变化年龄(βs= -0.21至-0.31,ps <.01)与酒精使用频率(βs= 0.14至0.31,ps <.001),大麻起始年龄之间存在显着关系。烟草使用量的变化率(β= 0.23,p <.01),烟草起始年龄和大麻使用频率的变化率(β= -0.14,p <.01)。在调整了起始年龄之后,观察到烟草和酒精的运动轨迹(r = 0.43,p <.0001)与酒精和大麻的运动轨迹(r = 0.20,p <.05)之间存在显着关联。结果突显了起始年龄和跨物质使用变化率之间的内部和交叉物质关系的差异。他们认为,物质使用轨迹的差异部分是由首次使用时的年龄造成的。

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